These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
Berberine is a chemical found in several plants including the European barberry, goldenseal, goldthread, Oregon grape, philodendron, and tree turmeric and belongs to a class of compounds called alkaloids. It is said to have powerful effects similar to that of a pharmacological nature and has been used for centuries in Chinese medicine. It is just now coming of age in modern nutritional medicine in the treatment of diseases such as diabetes.
How Does Berberine Work? Berberine is known to stimulate insulin secretion and to activate AMPK, an enzyme known to regulate cellular energy metabolism. Its primary actions are to:
Effectiveness of Berberine in Diabetic Patients: Berberine has been found to act in a similar manner as the commonly used diabetes drug Metformin. It is not clear whether metformin and berberine undertake all actions via the same mechanisms, or some via similar and other different mechanisms. While the severe adverse gastrointestinal side-effects that interfere with metformin compliance are generally absent in berberine treatment, treatment with both berberine and metformin (or other oral hypoglycemics) has been found to be superior in controlling glucose than either treatment alone.
Dosage and treatment duration may vary with the patient’s age. Data suggests that berberine therapy becomes unremarkable in treatments lasting more than 90 days or in amounts greater than 2 grams. Further clinical studies of longer duration are needed in this area. The most effective dose is 500 mg three times a day.
Because most anti-diabetic drugs cannot be used in patients with hepatic dysfunction, renal disease, and heart disease, this makes pharmacological therapy of type 2 diabetes complicated and the use of other nutraceuticals such as berberine more desirable.
Current studies have reported the significance of berberine against oxidative stress and inflammation in cells, elaborating its vital role in diabetes mellitus. Generally, a decrease in blood glucose level by 20–40% is reported in fasting patients treated with berberine alone, this effect resembles that of rosiglitazone and metformin treatment.
Application: Preliminary research from both animal and human studies indicate that berberine therapy in dosages of 500 mg three times per day may be an advantageous treatment for diabetes type 2 either alone or in conjunction with other hypoglycemics for optimal blood sugar control with minimal adverse side-effects.
The mechanisms of action of berberine mirror those of the common anti-diabetic drug metformin without the severe diarrhea side-effects that adversely affect medication compliance.
Further long-term studies are needed on human subjects to identify exact mechanisms of action and duration of treatment best utilized for long term blood sugar control of diabetes.
#berberine #AMPK #diabetes #blood sugar #type 2 diabetes #metformin
These statements have not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure or prevent any disease.
Many of us brush off common aches and pains treating them with ibuprofen and hoping the bothersome things will go away, but such practices are becoming costlier not only financially, but health-wise as well. It is not uncommon to hear stories of someone with diabetes putting off care for an infected toe because of lack of insurance and several weeks down the road the toe needs to be amputated.
Culinary medicine does not have a single philosophy as it is not dietetics or functional medicine, nor is it culinary arts or food science. It is, rather, a new evidence-based field in medicine that blends the art of food and cooking with the science of medicine. Culinary medicine is all about making evidence based decisions about the food we choose to eat and how we eat it so that we can prevent and treat disease while restoring optimal well-being.
As food is condition specific, the theory goes, different clinical conditions require different foods, beverages and manners of cooking as well as types of herbs used in seasoning such foods. Although special attention is paid to using the foods that the patient regularly eats or drinks, modifications are by nature necessary but designed to empower the patient to care for herself or himself safely, effectively, and happily with food and beverage as a primary care technique.
Special attention is paid to how food works in the body and how such foods can be made pleasurable to the patient so that cooking and eating are both a healthy and enjoyable experience.
According to one study, culinary medicine started trending in response to five factors:
Preliminary research regarding culinary medicine is encouraging. A longitudinal study among 627 medical students showed hands-on cooking and nutrition education vs. traditional education improved diet, attitudes, and competencies. Results from a small randomized controlled trial of patients with type 2 diabetes showed improvement in HbA1c, blood pressure, and cholesterol after following a Mediterranean diet cooking and nutrition curriculum provided by a medical school-based teaching kitchen.
Culinary medicine is an evidence based approach to food and lifestyle intervention. It encourages us to think of food as medicine, nutrition with cooking and necessity with creativity. The growing body of research supports the idea of food as medicine as more and more programs make successful groundbreaking efforts at making food a critical part of patients’ medical care.
Some doctor’s in communities are writing prescriptions for fresh vegetables and produce and vendors respond to the prescriptions with discounts on their products. Culinary medicine can be a beautiful community health initiative that the entire family can be involved in at all stages of the wellness/disease spectrum.
#culinary medicine #MNT #medical nutrition therapy #wellness
Thyroid supplements are generally taken by those who think they have sluggish thyroids, they are gaining weight for no reason or they have self-diagnosed themselves with hypothyroidism. The supplement market is eager to meet the needs of desperate consumers armed with only a handful of internet articles and a plethora of misinformation.
Here we will discuss the most common thyroid supplements and what they are designed to do and why a patient should not take these supplements without a doctor’s recommendation or upon a dietitian's recommendation.
Iodine is needed for the production of the thyroid hormone. Before the 1920’s iodine deficiency was a common problem, especially in the so-called “goiter” states where soil was especially depleted. However, the U.S. implemented a salt fortification program adding iodine to salt and thus forming iodized salt. Iodine deficiency dropped. Today, iodine deficiency in the United States is not the primary cause of hypothyroidism, but rather an autoimmune condition called Hashimoto’s is the cause of 80% of the nearly 20 million Americans who currently are hypothyroid.
In Hashimoto’s Disease (HD), iodine is often avoided. So, if someone with Hashimotos hypothyroidism supplements with iodine, the situation could be made worse as it may accelerate thyroid cell destruction. Research has shown that high doses of iodine can trigger Hashimoto’s in people who are genetically predisposed to Hashimoto’s and may perhaps have certain “vulnerabilities” like a selenium deficiency.
Selenium protects the thyroid from oxidative damage and without selenium a high iodine intake can destroy the thyroid. Iodine and selenium need to be in balance and selenium is the next most important hormone for thyroid health aside from iodine.
Taking selenium just because one thinks their thyroid is “sluggish” may not help the problem, but cover up a more serious one that need pharmacological and/or surgical intervention. Oftentimes we see patients struggle with self-perceived thyroid problems by supplementing with nutrients the thyroid needs, but giving selenium may hide an undiagnosed tumor, goiter or the synergy of nutrients needed to get the thyroid healed if it is truly sick. Both excessively high and excessively low selenium levels have proven damaging to the thyroid gland.
L-Tyrosine Most people have enough L-tyrosine in your body but occasionally a supplement is recommended if you have hypothyroidism. Be careful not to supplement on your own as too high of an L-tyrosine level can aggravate high blood pressure, manic symptoms and may interact with other medications.
Coleus Forskohlii This herb enhances the uptake of iodine into the cells and promotes the production of T3 and T4. Again the problem with this herb is the same as with supplementation with iodine.
Ashwagandha As a member of the nightshade family, those individuals with autoimmune conditions are to avoid products from this family. Grave’s Disease and Hashimoto’s Disease are both diseases of the autoimmune system and as such call for avoidance of this otherwise very beneficial herb.
Supplements should only be taken after consultation with a health professional. Seemingly wonderful products can be harmful if taken for the wrong reason or the wrong condition.
Not all supplements are safe. Supplements should be recommended by a Registered Dietitian after a complete medical nutritional assessment is done.